PF 06463922
[CAS 1454846-35-5]

Identification

• Classification: Biochemical >> Inhibitor >> Protein tyrosine kinase
• Name: PF 06463922
• Synonyms: (10R)-7-Amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile
• Molecular Formula: C₂₁H₁₉FN₆O₂
• Molecular Weight: 406.41
• CAS Registry Number: 1454846-35-5
• EC Number: 813-704-5

Properties

• Solubility: Practically insoluble (0.035 g/L) (25 °C), Calc.^*
• Density: 1.42±0.1 g/cm³ (20 °C 760 Torr), Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2014 ACD/Labs)

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Germ cell mutagenicity	Muta.	2	H341
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Reproductive toxicity	Repr.	2	H361
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400