6-Thioguanine
[CAS 154-42-7]

Identification

• Classification: API >> Antineoplastic agents >> Antimetabolite antineoplastic
• Name: 6-Thioguanine
• Synonyms: 2-Amino-6-purinethiol; 2-Amino-6-mercaptopurine; 2-Aminopurine-6(1H)-thione
• Molecular Formula: C₅H₅N₅S
• Molecular Weight: 167.19
• CAS Registry Number: 154-42-7
• EC Number: 205-827-2

Properties

• Melting point: 360 °C
• Water solubility: soluble

Safety Data

• Hazard Symbols: T
• Risk Statements: R25
• Safety Statements: S28A;S45

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	3	H301
Carcinogenicity	Carc.	2	H351
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410
Germ cell mutagenicity	Muta.	2	H341
Reproductive toxicity	Repr.	1A	H360
Skin irritation	Skin Irrit.	2	H315
Eye irritation	Eye Irrit.	2	H319
Specific target organ toxicity - single exposure	STOT SE	2	H371
Reproductive toxicity	Repr.	1B	H360
Acute toxicity	Acute Tox.	4	H302
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Carcinogenicity	Carc.	1A	H350
Germ cell mutagenicity	Muta.	1B	H340

• Transport Information: UN 2811