Plicamycin
[CAS 18378-89-7]

Identification

• Classification: API >> Antineoplastic agents >> Antibiotic antineoplastic agents
• Name: Plicamycin
• Synonyms: 2371; Antibiotic LA 7017; Aureolic acid; Mithracin; Mithramycin A; Mitramycin; NSC 24559; PA 144; Plicatomycin
• Molecular Formula: C₅₂H₇₆O₂₄
• Molecular Weight: 1085.15
• CAS Registry Number: 18378-89-7
• EC Number: 634-048-4

Properties

• Solubility: Very slightly soluble (0.11 g/L) (25 °C), Calc.^*
• Density: 1.48±0.1 g/cm³ (20 °C 760 Torr), Calc.^*
• Melting point: 181.5 °C^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2014 ACD/Labs)

^** "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US)

Safety Data

• Hazard Symbols: Xn
• Risk Statements: R22

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302
Eye irritation	Eye Irrit.	2	H319
Reproductive toxicity	Repr.	2	H361
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H312
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	3	H301
Acute toxicity	Acute Tox.	3	H331
Acute toxicity	Acute Tox.	3	H311
Specific target organ toxicity - single exposure	STOT SE	3	H335