Hydrochlorothiazide
[CAS 58-93-5]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyridine compound >> Chloropyridine
• Name: Hydrochlorothiazide
• Synonyms: 3,4-Dihydro-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine-1,1-dioxide; 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide; 3,4-Dihydrochlorothiazide
• Molecular Formula: C₇H₈ClN₃O₄S₂
• Molecular Weight: 297.73
• CAS Registry Number: 58-93-5
• EC Number: 200-403-3

Properties

• Melting point: 273-275 °C

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302
Skin sensitization	Skin Sens.	1	H317
Respiratory sensitization	Resp. Sens.	1	H334
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Carcinogenicity	Carc.	2	H351
Reproductive toxicity	Repr.	2	H361
Germ cell mutagenicity	Muta.	2	H341
Reproductive toxicity	Lact.	-	H362
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Eye irritation	Eye Irrit.	2	H319
Acute toxicity	Acute Tox.	4	H332
Skin irritation	Skin Irrit.	2	H315
Germ cell mutagenicity	Muta.	1B	H340
Specific target organ toxicity - single exposure	STOT SE	3	H335
Reproductive toxicity	Repr.	1B	H360
Serious eye damage	Eye Dam.	1	H318
Acute toxicity	Acute Tox.	4	H312
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410