阿霉素
[CAS 29042-30-6]

基本信息

• 产品名称: 阿霉素
• 英文名: Adriamycin
• 别名: (7S,9S)-7-[(2R,4S,5S,6S)-4-Amino-5-Hydroxy-6-Methyl-Tetrahydropyran-2-Yl]Oxy-6,9,11-Trihydroxy-9-(2-Hydroxyacetyl)-4-Methoxy-8,10-Dihydro-7H-Tetracene-5,12-Dione; (7S,9S)-7-[[(2R,4S,5S,6S)-4-Amino-5-Hydroxy-6-Methyl-2-Tetrahydropyranyl]Oxy]-6,9,11-Trihydroxy-9-(2-Hydroxy-1-Oxoethyl)-4-Methoxy-8,10-Dihydro-7H-Tetracene-5,12-Dione; (7S,9S)-7-[(2R,4S,5S,6S)-4-Amino-5-Hydroxy-6-Methyl-Tetrahydropyran-2-Yl]Oxy-9-Glycoloyl-6,9,11-Trihydroxy-4-Methoxy-8,10-Dihydro-7H-Tetracene-5,12-Quinone
• 分子式: C₂₇H₂₉NO₁₁
• 分子量: 543.53
• CAS 登录号: 29042-30-6
• 分子行输入简码 SMILES: [C@H]4(C3=C(C(=C2C(C1=CC=CC(=C1C(C2=C3O)=O)OC)=O)O)C[C@](C(CO)=O)(O)C4)O[C@H]5C[C@@H]([C@H](O)[C@@H](O5)C)N
• 国际化学标识码 InChI: 1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1
• 国际化学标识检索码 InChIKey: AOJJSUZBOXZQNB-TZSSRYMLSA-N

物理化学性质

• 密度: 1.6±0.1g/cm³ （计算值）
• 沸点: 810.3±65.0°C at 760 mmHg （计算值）
• 闪点: 443.8±34.3°C （计算值）

参考文献

• (1): Gonçalo J. L. BernardesThese authors contributed equally to this work., Raghavendra Kikkeri, Maha Maglinao, Paola Laurino, Mayeul Collot, Sung You Hong, Bernd Lepenies and Peter H. Seeberger. Design, synthesis and biological evaluation of carbohydrate-functionalized cyclodextrins and liposomes for hepatocyte-specific targeting, Org. Biomol. Chem., 2010, 8, 4987.